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Publications

The LPRC supports bold research that helps to improve the development and delivery of medicines, helping more people live healthier lives.

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K. Colston, S. Monsalve, S. Schneebeli*, "Structure-Based Modeling of Environment-Dependent Protonation States Across LNP Formulations with Atomistic CpHMD," Molecular Pharmaceutics, iss. 12, vol. 22, Oct 2025. DOI: https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.5c00348.

Mario de Lucio, Yu Leng, Atharva Hans, Ilias Bilionis, Melissa Brindise, Arezoo M Ardekani, Pavlos P Vlachos, and Hector Gomez, "Modeling large-volume subcutaneous injection of monoclonal antibodies with anisotropic porohyperelastic models and data-driven tissue layer geometries," Journal of the Mechanical Behavior of Biomedical Materials, vol. 138, Feb 2023. DOI: 10.1016/j.jmbbm.2022.105602.

John D Toaquiza Tubon, Omar Moreno-Flores, Vivek D Sree, and Adrian B Tepole, "Anisotropic damage model for collagenous tissues and its application to model fracture and needle insertion mechanics," Biomechanics and Modeling in Mechanobiolog, vol. 21, Dec 2022. DOI: 10.1007/s10237-022-01624-y.

Vivek D Sree, Arezoo Ardekani, Pavlos Vlachos, and Adrian Buganza Tepole, "The Biomechanics of Autoinjector-Skin Interactions During Dynamic Needle Insertion," Journal of Biomechanics, vol. 134, Mar 2022. DOI: 10.1016/j.jbiomech.2022.110995.

Ehsan Rahimi, Soroush Aramideh, Dingding Han, Hector Gomez, and Arezoo M Ardekani, "Transport and lymphatic uptake of monoclonal antibodies through subcutaneous injection," Microvascular Research, vol. 139, Jan 2022. DOI: 10.1016/j.mvr.2021.104228.

Yu Leng, Mario de Lucio, and Hector Gomez, "Using poro-elasticity to model the large deformation of tissue during subcutaneous injection," Computer Methods in Applied Mechanics and Engineering, vol. 384, Oct 2021. DOI: 10.1016/j.cma.2021.113919.

J. Zhang, J. Xu, J. G. Lim, J. K. G. Nolan, H. Lee, and C. H. Lee, "Wearable glucose monitoring and implantable drug delivery systems for diabetes management," Advanced Healthcare Materials, iss. 17, vol. 10, Sep 2021. DOI: 10.1002/adhm.202100194.

Minghe Li, Aleksandr Razumtcev, Ruochen Yang, Youlin Liu, Jiayue Rong, Andreas C. Geiger, Romain Blanchard, Christian Pfluegl, Lynne S. Taylor, and Garth J. Simpson, "Fluorescence-Detected Mid-Infrared Photothermal Microscopy," Journal of the American Chemical Society, iss. 29, vol. 143, Jul 2021. DOI: 10.1021/jacs.1c03269.

X. Zhong, J. Eshraghi, P. P. Vlachos, S. Dabiri, and A. M. Ardekani., "A model for a laser-induced cavitation bubble," International Journal of Multiphase Flow, iss. 132, Nov 2020. DOI: 10.1016/j.ijmultiphaseflow.2020.103433.

Zhongwang Dou, Javad Eshraghi, Tianqi Guo, Jean-Christophe Veilleux, Kevin H. Duffy, Galen H. Shi, David S. Collins, Arezoo M. Ardekani, and Pavlos P. Vlachos, "Performance characterization of spring actuated autoinjector devices for Emgality and Aimovig," Current Medical Research and Opinion, iss. 8, vol. 36, Jun 2020. DOI: 10.1080/03007995.2020.1783219.